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专利名称：SUPPOSITORIES发明人：YOKOMACHI, HIDEHARU申请号：EP97924286申请日：19970529公开号：EP0916340A4公开日：20000628
摘要：The inventor provides suppositories comprising as the active ingredient 6-amino-5-chloro-1-isopropyl-2-(4-methyl-1 -piperazinyl) benzimidazole (I). Thesesuppositories are expected to exert drug effects based on serotonin3 antagonisticactivity when administered rectally. More particularly, these suppositories are useful asantiemetic agents for vomiting accompanying chemotherapy for cancer or remedies forirritable bowel syndrome based on the serotonin3 antagonistic activity. Thesesuppositories provide also excellent storage stability of benzimidazole derivative (I).
申请人：KANEBO, LTD.
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