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专利名称：METHOD FOR PREVENTING AND TREATING
RENAL DISEASE
发明人：Alessia Fornoni,Sandra Merscher-Gomez申请号：US14967831申请日：20151214
公开号：US20160220600A1公开日：20160804
摘要：Assays, methods and kits for predicting a subject's (e.g., human) risk of primaryglomerulopathy, secondary glomerulopathy or recurrence (e.g., post-transplantrecurrence) of any glomerular disease include examining cells for the presence orabsence of cytoskeletal disruptions or rearrangements and examining cells formodulation of expression and/or activity of markers such as SMPDL-3b. Assays forpredicting if a diabetic subject will develop kidney disease or a patient with FSGS willdevelop recurrent disease after transplant also include examining cells for the presenceor absence of cytoskeletal disruptions or rearrangements and examining cells formodulation of expression and/or activity of markers such as SMPDL-3b. Also describedherein are compositions and methods for treating and preventing the aforementioneddisorders.
申请人：L & F Research LLC
地址：Miami FL US
国籍：US
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